Have you misplaced your keys again this week? Forgotten
to put the cat out? Or ever climbed the stairs and walked into your
bedroom only to find that you can’t remember what you are
there for?
We all experience short memory lapses and so called ‘brain
blanks’ from time to time, but how many of us worry that
these could be the early signs of a failing memory?
Dementia currently affects 750,000 people in the UK and one
person in twenty over the age of 65 suffers from some form of loss
of brain function due to a specific condition or disease. Symptoms
include loss of memory, confusion and problems with speech and
understanding. Alzheimer’s is the most common form and
accounts for 55% of all cases of dementia. The number is steadily
increasing and the British Alzheimer’s Society believes that
careful planning for the future is needed now if we are to avoid a
major ‘epidemic’.
This could be difficult when there is no way of knowing if you
are at risk. Currently there is no existing method of telling who
may develop dementia other than a genetic test for one very rare
form of the condition. But Swedish scientists have devised a test
(opposite), recently published in the prestigious medical journal,
The Lancet, which they believe could reveal your level of risk.
The test, which assesses physical and lifestyle factors,
indicates a risk score which, the researchers claim, predicts
dementia occurrence with approximately 70% accuracy (although
results still need to be validated in further studies).
The seven test questions are based on a Finnish study that
revealed certain midlife risk factors associated with dementia.
Initially, 1,409 middle aged people were studied and then assessed
twenty years later for symptoms of dementia. Four per cent of those
assessed were affected and the results indicated that the chances
of developing dementia were significantly linked to certain
factors.
These results were used to develop a simple score system to help
predict the likelihood of developing dementia in later life. The
team hopes that the test can be used not as definite prediction of
disease, but as a simple tool to indicate risk and encourage
lifestyle changes in those with the highest danger.
Rebecca Wood, chief executive of Alzheimer’s Research
Trust, told the BBC: ‘It (the test) is still a somewhat blunt
instrument because it picks up too many people who may not develop
dementia, so much more work is needed to improve and validate its
results.’ She was, however, excited at the prospect of being
able to identify those at higher risk who might be able to
introduce lifestyle changes to reduce it.
The most important one you can make is to improve your
nutrition. Numerous studies highlight links between the onset of
dementia and the intake of excess salt and saturated fat. Eating
less saturated animal fats can reduce excess weight gain and also
help to maintain lower cholesterol and bloodpressure levels, three
major risk factors associated with dementia.
Mr Ryrie, research programme director at the Mental Health
Foundation, said: ‘If people want to protect themselves
against dementia, they should limit the amount of salt and
saturated fat they consume and eat more foods containing essential
B vitamins, omega 3 and zinc.’
Vitamins B6 and B12, found abundantly in oily fish, meat and
eggs, are now widely recommended to people over the age of
fifty-five as they have been shown to combat elevated homocysteine
levels, an amino acid linked to memory loss and dementia.
Omega 3 fish oils are a rich source of the essential fatty acid,
DHA (docosahexaenoic acid) which forms one of the most important
components of the brain and is essential for its function. Brain
cell membranes rich in DHA are able to communicate quickly with
each other, as DHA plays a significant role in facilitating their
messages. Low levels of DHA can slow the efficiency of these
messages and in older people, deficiency has been linked with
memory loss and mood swings.
As DHA cannot be readily manufactured by the body, omega 3 fatty
acids need to be obtained from oily fish in the diet or from
supplementation.
Zinc is also an integral part of the communication structure
between nerve cells, facilitating normal brain function. Only 50%
of people obtain the 15mg recommended daily allowance of dietary
zinc and deficiencies have been linked to impairments in cognitive
function.
Other specific nutrients may also benefit cognitive function.
Clinical evidence suggests that ginkgo biloba has beneficial
effects. A study involving 34 post-menopausal women treated with
120mg gingko daily performed significantly better in memory tests
than those who received a placebo1. The benefits of
ginkgo are attributed to its widening of the blood vessels, which
allows improved flow to the brain, as well as its antioxidant
properties, which help to protect the brain against cell-damaging
‘free radical’ molecules.
Phosphatidyl serine, naturally present in brain-cell membranes,
also helps to maintain healthy cognitive function, playing a vital
part in the transfer of messages between the cells.
During the last decade, we have come to realise that certain key
nutrients have a special function, at optimal levels of intake, in
maintaining brain health and preventing age-related cognitive
decline’ said Mr Ryrie.
As with the prevention of many diseases, a healthy diet,
adequate nutrition and regular exercise are vital in reducing the
major risk factors associated with dementia.
1Hartley et al; Pharmacol Biochem Behav. 2003
Jun; 75 (3):711-20.
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