Did cavemen get arthritis?

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We often hear that the ideal diet to prevent all chronic diseases, including arthritis, is the Stone-Age’ Diet, which was believed to be based on the meat of hunted animals and the leaves, roots, seeds and fruits of gathered wild plants.

Did the ancient Stone-Age’ diet really combine the best features of what we now call healthy eating’? In this article, the links between evolution, nutrition, dietary change and arthritis are explored in relation to archaeological evidence.

Arthritis in history

The earliest known case of human arthritis was found in a cave at La

Chapelle-aux-Saints, France in 1908. It was the bent-over frame of a Neanderthal Old Man’, who lived 60,000 years ago. His ape-like spine was responsible for the myth that the Neanderthals were one of the missing links in human evolution. But subsequent finds suggest that they were regular humans who just looked a little different from us and that their skeletal deformities were due to diet.

Scanning forward to 4500 BC, we find that the bones of native Americans from Tennessee showed traces of arthritis. Indeed, evidence of arthritis has been found throughout history, from the mummies of Egyptian Pharaohs to the citizens of Ancient Rome: even Julius Caesar had it. There are also references to the condition in the Bible and in Shakespeare’s plays.

So, although arthritis is not new, it is on the increase. Obviously, we have no idea of the incidence of arthritis in prehistory, as skeletal relics are randomly preserved and many bear no arthritic traces. However, in modern-day Britain, more than 15% of adults have long-term arthritic conditions.

Diet and human evolution

Human beings are believed to have evolved in east Africa between 100-200,000 years ago and the human genome has hardly changed since. Evolution of a species is driven by its environment, including food availability.

So what foods were available for humans as they evolved? One thought is that the environment presented the Hunter-Gatherer with a combination of meats and plant foods, offering a diet low in fat and high in fibre1. Intakes of vitamins, minerals and phyto-chemicals, such as flavonoids, would have been much higher than today. Did this provide adequate nutriment for the evolution of the human big brain’? Professor Michael Crawford, of the Institute of Brain Chemistry in London, thinks not he considers that an additional factor was necessary.

According to Prof. Crawford, humans were unlikely to have evolved a large, complex, metabolically expensive brain in an environment which did not provide abundant omega 3 fatty acids from seafood. He argues that the big brain, with its high content of omega 3 fatty acids, must have evolved in a marine environment. In fact, in his book, The driving force of human evolution2, Prof. Crawford says that he is convinced that fish and shellfish were key features of the Stone-Age’ diet, along with meat from wild animals and plant foods. Perhaps it is no coincidence, therefore, that abundant remains of fish bones and shellfish have been found at many fossil sites of early hominoids in Africa.

Diet in transition

Human beings continued to eat fish after their migrations from Africa. Indeed, 12,000-year-old human remains from north Wales show that a third of protein intake was derived from sea foods3. However, land-locked human groups were less fortunate. During the Ice Age, Neanderthals lived in dark caves and probably suffered from vitamin D deficiency due to a lack of sunlight. Hence, if their diet was low in fish, they not only missed out on its rich vitamin D content, but also on its omega 3 fatty acids, with consequent risk of the development of soft, deformed bones and arthritic joints. Throughout time, other land-locked groups may have been similarly disadvantaged, giving rise to increased arthritis risk among humans bereft of a marine environment.

Diets changed radically with the introduction of cooking and agriculture about 10,000 years ago. Further change was wrought during the Industrial Revolution, when the refining of grains and edible oils was introduced. Although both these developments impacted on overall nutrient intake, no diet has moved further away from the Stone-Age diet than that of today.

Back to nature

There seems to be little doubt that many current health problems result from a mismatch between our genetically determined nutritional requirements and our modern diet. According to numerous studies1, the Stone-Age diet, high in fruit, vegetables and fish, is still the best for modern humans to reduce their risk of chronic diseases. To mimic this diet, we need to avoid rich food and eat plenty of fruit, vegetables and high-fibre foods to maintain a healthy digestive system and a healthy weight. Furthermore, research shows that, together with an adequate supply of vitamin D, calcium and magnesium, plant foods help to strengthen bones against risk of fracture and omega 3 fatty acids from oily fish help to moderate the inflammatory process which gives rise to arthritis.

Interestingly, glucosamine and chondroitin (now widely used as supplements to reduce the symptoms of arthritis) are both sourced from marine life. The health benefits of seafood may explain why Greenland Inuits have one of the lowest rates of arthritis in the world.

Conclusion

There is a mismatch between the diet of our prehistoric ancestors and our current one. Since our genes have hardly changed over the millennia, we are still better adapted to a Stone-Age diet than to modern fare. To live a long healthy life, most of us need to make radical changes in our diet and bridge any remaining gaps in our nutrient intakes with appropriate dietary supplements.

References

1. Cordain L et al. 2005. Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr. 81:341-54.

2. Crawford M, Marsh D. 1989. The Driving Force: Food, Evolution and the Future. William Heinemann, London.

3. Richards MP et al. 2006. Isotope evidence for the intensive use of marine foods by Late Upper Palaeolithic humans. J Hum Evol. 51:440-2.

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Dr Ann Walker

Dr Ann Walker 

Dr Ann Walker is Senior Lecturer in Human Nutrition at The University of Reading. She is a member of the national Institute of Medical Herblists and of the College of Practitioners of Phytotherapy. She is the author of several books on human nutrition. 

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