With all the positive news in the media regarding statins, hands up those of you that take them? Now hands up those of you that are also taking co enzyme Q10? Well for those of you who raised your hand to the former but not the latter, you need to read this.
Co enzyme Q10 (CoQ10) is a vitamin-like substance produced naturally in the body and found in some foods, that is vital for energy production in cells. It is especially important in skeletal and heart muscle cells that are actively contracting. Statin medication (eg. atorvastatin and simvastatin) is generally taken to reduce levels of unwanted (LDL) cholesterol in the body. However, its mechanism not only reduces the production of cholesterol in the body, but also the production of CoQ10. In fact, taking a statin can halve your natural production of CoQ10 within just two weeks. The reduction of CoQ10 can have a significant impact on cardiovascular function. Studies suggest that 20mg of simvastatin reduced the level of plasma CoQ10 by 42.9% over a period of 3 months.
1 This reduction in vital levels of CoQ10 can reduce its protective ability against oxidative stress in areas such as the arteries. This reduced protection can play a significant contributory role in the development of atherosclerosis.
What does this mean?
With statins being prescribed to around 2.5 million people in the UK each year, there is a growing population deficient in
CoQ10. Its nomenclature ‘Ubiquinone’, translated literally as ‘everywhere’, gives you an indication of how important CoQ10 really is. Its vital role in energy production means that should our stores run into ‘red’ you can experience debilitating symptoms such as a lack of energy, muscle aches and pains and, over a period of time, heart problems, including heart failure. Although the body is able to produce its own supply of CoQ10, blood concentrations of this nutrient peak at 20 years of age and it is not long into our life that demand starts to outweigh supply. Supply from foods ‘rich’ in CoQ10 are unable to provide the therapeutic levels that the body needs in a state of deficiency. Add to this declining levels as a result of food processing and you will be able to see why many medical professionals, as well as those in the natural health field, agree that co enzyme Q10 supplementation is essential for those on statin medication. Comprehensive European Studies demonstrate that combining CoQ10 supplementation with statins preserved the level of CoQ10 in the blood without affecting the cholesterol lowering efficacy of statins. Indeed one study suggested a potential additive or synergistic relationship between co enzyme Q10 and the effectiveness of statins and the progression of cardiovascular disease.
2 So take care of your heart by adopting the future of integrated medicine and ensure that you do the best for yourself with a regular
co enzyme Q10 supplement, as well as your statin.
Recommended doses of CoQ10 for these benefits have been shown to be between
60mg-100mg, dependant on the amount of statin medication. Always discuss any
supplements you are taking with your GP or pharmacist.
1. Passi S et al; Biofactors 18 (2003) 113-124
2. Bliznakov EG. Biomed Pharmacother 2002;56;56-9.
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