Supplement Spotlight: Vitamin C

Oranges

What is vitamin C? Vitamin C is a water-soluble vitamin which cannot be stored in the body, so a regular intake is essential. Most animals make their own, but we lack the enzyme (L-gulonolactone oxidase) needed for its synthesis. This is probably because cavemen obtained good amounts from berries and green leaves, so there was little evolutionary pressure to acquire this metabolic trick.

Requirements

Different authorities have suggested different levels of adequate intake for vitamin C that range between 30-100mg per day. These were based on criteria such as prevention of deficiency disease (scurvy), turnover rates or tissue saturation. But when vitamin C function is taken into account, higher intakes are justified. Adult goats, for example, which are similar in weight to man, produce between 2g and 13g per day, depending on their level of stress and illness. Higher doses of vitamin C appear to have a therapeutic effect that may protect against common illnesses. Smokers and those with diabetes need twice as much vitamin C as non-smokers and those with normal glucose control, as their metabolism generates many more free radicals which consume vitamin C more rapidly.

Cardiovascular health

Vitamin C is the main antioxidant in body fluids and regenerates vitamin E, which protects lipids such as cell membranes. Vitamin C increases levels of beneficial HDL-cholesterol and reduces uptake of harmful LDL-cholesterol by the scavenger cells which deposit cholesterol in artery walls. As well as protecting against hardening and furring up of the arteries, vitamin C improves dilation of diseased arteries, lowers blood pressure and reduces levels of fibrinogen­ a circulating protein that increases the likelihood of blood clots. It therefore helps to protect against heart disease and stroke.

Immunity

High levels of vitamin C block the replication of viruses inside cells to lower the frequency and severity of the common cold. It also reduces the duration of herpes cold sores. Its antihistamine action is helpful against allergies.

Joint health

Vitamin C is essential for the synthesis of collagen, a major structural protein in bone and cartilage. It reduces cartilage loss and disease progression in osteoarthritis, while its anti-inflammatory action reduces joint inflammation. 

Bone health

Vitamin C stimulates bone-building cells (osteoblasts), enhances vitamin D activity and boosts calcium absorption to improve bone mineral density and reduce the risk of osteoporosis.

Types of vitamin C supplements available

Vitamin C with Bioflavonoids: these natural antioxidants found in fruits such as oranges, rose hips and acerola cherries increase absorption of vitamin C and work with it to strengthen body tissues and reduce inflammation.

Vitamin C sustained release: provides a constant delivery of vitamin C over six to eight hours so blood levels stay consistently higher for longer.

Effervescent Vitamin C: dissolves in water to produce a pleasant-flavoured drink for rapid absorption.

Ester-C: contains the active, non-acidic, breakdown products of vitamin C which are more rapidly absorbed into cells. It does not cause indigestion at higher doses

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Dr Sarah Brewer

Dr Sarah Brewer 

Sarah Brewer graduated as a doctor from Cambridge University in 1983. She was a full-time GP for five years and now works in hospital medicine. She is the author of 40 books and writes widely on all aspects of health including complementary medicine. 

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