The supplement is made with cetylated fatty acids (CFAs) extracted from monounsaturated fats in olive oil and is often taken with the supplement glucosamine which supports joint health. CFAs used in Celadrin® are absorbed quickly by the body and noted for their fast-acting effects.
Dr Sarah Brewer says: ‘Celadrin® may improve lubrication of joints and provide a reduction in pain. For anyone suffering with joint pain, this is potentially a really useful supplement, recognised for providing quick results, particularly if used in conjunction with glucosamine supplements.’
What does Celadrin® do?
Scientists believe CFAs in Celadrin® are stored in cell membranes and may have a lubricating effect on joints, improving flexibility and resilience. CFAs may also improve the body’s production of prostaglandins, hormone-like substances that regulate your immune system and fight joint inflammation.
CFAs are also believed to have potent natural, anti-inflammatory, pain-killing properties. These are thought to block the action of an enzyme called 5-lipoxygenase which produces highly inflammatory substances involved in the development of a number of chronic diseases including asthma, hardening and furring-up of the arteries, and joint damage in osteoarthritis and rheumatoid arthritis.
CFAs are believed to be useful for relieving pain and stiffness in people suffering with osteoarthritis, the most common type of arthritis, caused by the cartilage which cushions the joints wearing thinner.
A third of people aged over 45, a total of 8.75 million people a year in the UK, see their GP about osteoarthritis symptoms which most commonly affect the hip, knee and finger joints.
A study in the prestigious Journal of Rheumatology conducted on people with chronic osteoarthritis of the knee found those treated with a CFAs supplement over 68 days showed an improvement in knee range and overall function, compared to those given a placebo.
Another trial carried out in the US involved 40 patients with osteoarthritis of the knee treated with either a CFA cream or a placebo cream. Those treated with the CFA cream reported significant benefits including a marked improvement in climbing stairs and standing up from a sitting position.
CFAs may also ease pain caused by muscular problems. One study involving patients suffering with myofascial pain syndrome, a chronic condition which causes pain in seemingly unrelated areas of the body, found those using a CFAs cream twice a day reported greater and faster relief from neck pain compared to the placebo group.
Getting CFAs from your diet
Celadrin® is a special blend of CFAs and not available from dietary sources. Taking a supplement or applying Celadrin® cream is therefore the only way you can get CFAs.
No serious side effects have been reported, although interactions with other medications have not been studied.
There is some anecdotal evidence suggesting smoking and caffeine could interfere with the effectiveness of CFAs.
If you are vegetarian or vegan, bear in mind some CFAs in supplements are derived from animal sources, so choose vegetarian and vegan versions.
There is no official UK or EU recommended daily intake, but 1 to 2 525mg tablets of Celadrin® can be taken daily. Celadrin® cream should be applied in a generous layer and rubbed in until fully absorbed.